Pain is the primary cause of disability in the United States. The NCHS estimates that as many as one in four Americans suffer pain lasting longer than twenty-four hours. ​Enduring pain is often an unintended consequence of treatments like cancer therapy, and it frequently accompanies conditions such as depression, post-traumatic stress disorder, and anxiety. In some cases, pain itself becomes a relentless chronic disease. One of the challenges faced by healthcare professionals is the inherently subjective nature of pain; its measurement defies conventional criteria and relies solely on the patient’s personal experience. Nonetheless, ongoing research is pioneering innovative methods to comprehend and assess pain, aiming to revolutionize the way we understand and address this complex aspect of human health.